Leonard Calabrese, DO

Leonard H. Calabrese, DO, heads Cleveland Clinic’s section of Clinical Immunology and manages its Clinical Immunology Clinic. He specializes in diseases of the immune system—in particular, immunodeficiency diseases such as human immunodeficiency virus (HIV) and other chronic viral infections, which are the subject of both clinical care and investigation. Dr. Calabrese is also co-director of the Center for Vasculitis Care and Research and has a particular interest in vascular inflammatory disease of the central nervous system.

A graduate of the Kansas City University of Medicine and Biosciences, Dr. Calabrese performed his internal medicine training at Cleveland Clinic in Ohio, followed by a fellowship in rheumatic and immunologic disease. He has been a staff member in Cleveland Clinic’s Department of Rheumatic and Immunologic Diseases since 1980.

Recipient of numerous awards and honors, Dr. Calabrese has received an honorary Doctorate of Humane Letters from the Kansas City University of Medicine and Biosciences, the Phillips Medal of Public Service from the Ohio University College of Osteopathic Medicine, the Bruce Hubbard Stewart Award for Humanitarianism, and the Leonard Tow Humanism in Medicine award from the Arnold P. Gold, MD, Foundation. He holds the RJ Fasenmyer Chair of Clinical Immunology and is the director of the RJ Fasenmyer Center for Clinical Immunology. When he was awarded the Theodore F. Classen, DO, Chair in Osteopathic Research and Education in 2008, he became the first dual-chair holder in Cleveland Clinic history.

Dr. Calabrese is a member of many professional societies, including the American Association of Immunology, the Clinical Immunology Society, the International AIDS Society, and the American Osler Society. He is a fellow of the American College of Rheumatology, the American College of Physicians, and the American College of Sports Medicine.

Dr. Calabrese has lectured nationally and internationally on the subjects of HIV, immunology, and rheumatology and is the author of more than 300 published, peer-reviewed articles, book chapters, and reviews.